Demographic and Clinical Patterns of Rheumatoid Arthritis in an Emirati Cohort from United Arab Emirates
Identifieur interne : 000901 ( Main/Exploration ); précédent : 000900; suivant : 000902Demographic and Clinical Patterns of Rheumatoid Arthritis in an Emirati Cohort from United Arab Emirates
Auteurs : Rajaie Namas ; Abhay Joshi ; Zarmeena Ali ; Jamal Al Saleh ; Mohammed AbuzakoukSource :
- International Journal of Rheumatology [ 1687-9260 ] ; 2019.
Abstract
This retrospective cohort study aimed to assess the demographic and clinical characteristics of rheumatoid arthritis (RA) in Emirati patients attending Cleveland Clinic Abu Dhabi, a large tertiary center in the Middle East. In this study, 414 Emirati patients with RA were evaluated over a 3-year period from April 2015 to April 2018. All patients fulfilled the 2010 RA ACR/EULAR criteria and were assessed for demographic and clinical characteristics. The estimated RA prevalence rate in our population cohort was 2.72%. Females showed predominance (80%) with a higher body mass index (31.4 ± 6.61,
Url:
DOI: 10.1155/2019/3057578
PubMed: 31662761
PubMed Central: 6778867
Affiliations:
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Ali</name><affiliation><nlm:aff id="I1">Division of Rheumatology, Department of Internal Medicine, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE</nlm:aff><wicri:noCountry code="subfield">UAE</wicri:noCountry></affiliation></author><author><name sortKey="Al Saleh, Jamal" sort="Al Saleh, Jamal" uniqKey="Al Saleh J" first="Jamal" last="Al Saleh">Jamal Al Saleh</name><affiliation><nlm:aff id="I2">Dubai Hospital, Dubai, UAE</nlm:aff><wicri:noCountry code="subfield">UAE</wicri:noCountry></affiliation></author><author><name sortKey="Abuzakouk, Mohammed" sort="Abuzakouk, Mohammed" uniqKey="Abuzakouk M" first="Mohammed" last="Abuzakouk">Mohammed Abuzakouk</name><affiliation><nlm:aff id="I1">Division of Rheumatology, Department of Internal Medicine, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE</nlm:aff><wicri:noCountry code="subfield">UAE</wicri:noCountry></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">31662761</idno><idno 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type="wicri:Area/Main/Exploration">000901</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Demographic and Clinical Patterns of Rheumatoid Arthritis in an Emirati Cohort from United Arab Emirates</title><author><name sortKey="Namas, Rajaie" sort="Namas, Rajaie" uniqKey="Namas R" first="Rajaie" last="Namas">Rajaie Namas</name><affiliation><nlm:aff id="I1">Division of Rheumatology, Department of Internal Medicine, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE</nlm:aff><wicri:noCountry code="subfield">UAE</wicri:noCountry></affiliation></author><author><name sortKey="Joshi, Abhay" sort="Joshi, Abhay" uniqKey="Joshi A" first="Abhay" last="Joshi">Abhay Joshi</name><affiliation><nlm:aff id="I1">Division of Rheumatology, Department of Internal Medicine, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE</nlm:aff><wicri:noCountry code="subfield">UAE</wicri:noCountry></affiliation></author><author><name sortKey="Ali, Zarmeena" sort="Ali, Zarmeena" uniqKey="Ali Z" first="Zarmeena" last="Ali">Zarmeena Ali</name><affiliation><nlm:aff id="I1">Division of Rheumatology, Department of Internal Medicine, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE</nlm:aff><wicri:noCountry code="subfield">UAE</wicri:noCountry></affiliation></author><author><name sortKey="Al Saleh, Jamal" sort="Al Saleh, Jamal" uniqKey="Al Saleh J" first="Jamal" last="Al Saleh">Jamal Al Saleh</name><affiliation><nlm:aff id="I2">Dubai Hospital, Dubai, UAE</nlm:aff><wicri:noCountry code="subfield">UAE</wicri:noCountry></affiliation></author><author><name sortKey="Abuzakouk, Mohammed" sort="Abuzakouk, Mohammed" uniqKey="Abuzakouk M" first="Mohammed" last="Abuzakouk">Mohammed Abuzakouk</name><affiliation><nlm:aff id="I1">Division of Rheumatology, Department of Internal Medicine, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE</nlm:aff><wicri:noCountry code="subfield">UAE</wicri:noCountry></affiliation></author></analytic><series><title level="j">International Journal of Rheumatology</title><idno type="ISSN">1687-9260</idno><idno type="eISSN">1687-9279</idno><imprint><date when="2019">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>This retrospective cohort study aimed to assess the demographic and clinical characteristics of rheumatoid arthritis (RA) in Emirati patients attending Cleveland Clinic Abu Dhabi, a large tertiary center in the Middle East. In this study, 414 Emirati patients with RA were evaluated over a 3-year period from April 2015 to April 2018. All patients fulfilled the 2010 RA ACR/EULAR criteria and were assessed for demographic and clinical characteristics. The estimated RA prevalence rate in our population cohort was 2.72%. Females showed predominance (80%) with a higher body mass index (31.4 ± 6.61, <italic>P</italic> = 0.0001) compared to males (28.8 ± 6.03, <italic>P</italic> = 0.0001). The most frequent comorbidity observed was dyslipidemia (43.5%) followed by hypertension (37.9%), diabetes mellitus (34.5%), and gastroesophageal reflux disease (33.1%). Xerophthalmia was the most frequent extra-articular manifestation. Rheumatoid factor and anti-citrullinated peptide were detected in 63.3% and 41.5% patients, respectively, while both were present in 33.3% of patients. Methotrexate, adalimumab, and rituximab were the most frequently prescribed disease modifying agents. In this study, we describe disease features that are unique to United Arab Emirates (UAE) patients and demonstrate that RA has a significant disease burden. Our findings highlight the need for a RA national registry to improve the quality of care of these patients in UAE.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Angelotti, F" uniqKey="Angelotti F">F. Angelotti</name></author><author><name sortKey="Parma, A" uniqKey="Parma A">A. Parma</name></author><author><name sortKey="Cafaro, G" uniqKey="Cafaro G">G. Cafaro</name></author><author><name sortKey="Capecchi, R" uniqKey="Capecchi R">R. Capecchi</name></author><author><name sortKey="Alunno, A" uniqKey="Alunno A">A. Alunno</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Teh, C L" uniqKey="Teh C">C. L. Teh</name></author><author><name sortKey="Wong, J S" uniqKey="Wong J">J. S. 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Jamshidi</name></author><author><name sortKey="Banihashemi, A T" uniqKey="Banihashemi A">A. T. Banihashemi</name></author><author><name sortKey="Roknsharifi, S" uniqKey="Roknsharifi S">S. Roknsharifi</name></author><author><name sortKey="Akhlaghi, M" uniqKey="Akhlaghi M">M. Akhlaghi</name></author><author><name sortKey="Salimzadeh, A" uniqKey="Salimzadeh A">A. Salimzadeh</name></author><author><name sortKey="Davatchi, F" uniqKey="Davatchi F">F. Davatchi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Davatchi, F" uniqKey="Davatchi F">F. Davatchi</name></author><author><name sortKey="Banihashemi, A" uniqKey="Banihashemi A">A. Banihashemi</name></author><author><name sortKey="Gholami, T J" uniqKey="Gholami T">T. J. Gholami</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Almoallim, H M" uniqKey="Almoallim H">H. M. Almoallim</name></author><author><name sortKey="Alharbi, L A" uniqKey="Alharbi L">L. A. Alharbi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Al Ghamdi, A" uniqKey="Al Ghamdi A">A. Al-Ghamdi</name></author><author><name sortKey="Attar, S M" uniqKey="Attar S">S. M. Attar</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list></list><tree><noCountry><name sortKey="Abuzakouk, Mohammed" sort="Abuzakouk, Mohammed" uniqKey="Abuzakouk M" first="Mohammed" last="Abuzakouk">Mohammed Abuzakouk</name><name sortKey="Al Saleh, Jamal" sort="Al Saleh, Jamal" uniqKey="Al Saleh J" first="Jamal" last="Al Saleh">Jamal Al Saleh</name><name sortKey="Ali, Zarmeena" sort="Ali, Zarmeena" uniqKey="Ali Z" first="Zarmeena" last="Ali">Zarmeena Ali</name><name sortKey="Joshi, Abhay" sort="Joshi, Abhay" uniqKey="Joshi A" first="Abhay" last="Joshi">Abhay Joshi</name><name sortKey="Namas, Rajaie" sort="Namas, Rajaie" uniqKey="Namas R" first="Rajaie" last="Namas">Rajaie Namas</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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